Wakasugi H, Nakayama K, Abe M, Hara Y, Ibayashi H
Gastroenterol Jpn. 1976;11(4):374-9. doi: 10.1007/BF02777379.
Pancreozymin-secretin test (PS test) and intestinal absorption tests were performed in 21 patients with chronic calcific pancreatitis and 32 patients with chronic noncalcific pancreatitis to evaluate exocrine functions of the pancreas. And the following results were confirmed. (1) Fecal fat excretion increased in 33% of chronic pancreatitis (47% of calcific pancreatitis and 25% of noncalcific pancreatitis). Serum carotene leves showed significantly low levels in 44% of chronic pancreatitis (67% of calcific pancreatitis and 27% of noncalcific pancreatitis). (2) D-xylose tolerance test was abnormally low in only 6% of chronic pancreatitis, but Schilling test was evaluated abnormally low in 29% of chronic pancreatitis (50% of calcific pancreatitis and 11% of noncalcific pancreatitis). (3) Fecal fat excretion increased in cases of severe exocrine insufficiency of the pancreas with decreased amylase output and decreased maximum bicarbonate concentration in PS test. (4) Correlation of fecal fat excretion to maximum bicarbonate concentration was statistically significant, but those to amylase output or volume of pancreatic juice were not significant. (5) Antacid drugs combined with pancreatic extracts seems to be indispensable in the treatment of chronic pancreatitis as far as malabsorption in chronic pancreatitis is concerned.
对21例慢性钙化性胰腺炎患者和32例慢性非钙化性胰腺炎患者进行了促胰液素-促胰酶素试验（PS试验）和肠道吸收试验，以评估胰腺的外分泌功能。并证实了以下结果。（1）33%的慢性胰腺炎患者粪便脂肪排泄增加（钙化性胰腺炎患者中为47%，非钙化性胰腺炎患者中为25%）。44%的慢性胰腺炎患者血清胡萝卜素水平显著降低（钙化性胰腺炎患者中为67%，非钙化性胰腺炎患者中为27%）。（2）仅6%的慢性胰腺炎患者D-木糖耐量试验异常降低，但29%的慢性胰腺炎患者希林试验评估异常降低（钙化性胰腺炎患者中为50%，非钙化性胰腺炎患者中为11%）。（3）在胰腺外分泌功能严重不足且PS试验中淀粉酶分泌量减少和最大碳酸氢盐浓度降低的情况下，粪便脂肪排泄增加。（4）粪便脂肪排泄与最大碳酸氢盐浓度的相关性具有统计学意义，但与淀粉酶分泌量或胰液量的相关性不显著。（5）就慢性胰腺炎的吸收不良而言，抗酸药物联合胰酶提取物似乎是慢性胰腺炎治疗中不可或缺的。
