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因产前感染淋巴细胞性脉络丛脑膜炎病毒所致的脑积水。

Hydrocephalus due to prenatal infection with the lymphocytic choriomeningitis virus.

作者信息

Sheinbergas M M

出版信息

Infection. 1976;4(4):185-91. doi: 10.1007/BF01638922.

DOI:10.1007/BF01638922
PMID:1017876
Abstract

The results are presented of serological examinations in a total of 4235 subjects including blood donors (341 persons), pregnant women (1784), newborns (833), patients with malignant tumours (248), patients with influenza-like diseases (548), patients with abacterial meningitis (295), infants under one year with hydrocephalus (40), infants under two years with other nervous system diseases (110), mothers of seropositive children with hydrocephalus (12) and mothers of seronegative children with hydrocephalus (24). The investigations revealed 16 cases of serologically confirmed prenatal lymphocytic choriomeningitis virus infection. Immunofluorescent antibody to this virus was detected in the children in most cases at high titers and in their mothers at moderate and low titers. In 14 children hydrocephalus was manifest, one child was suffering from infantile cerebral palsy, and one child from congenital right side blepharoptosis. Foci of chorioretinal degeneration were found in 14 patients. During pregnancy six mothers had an influenza-like illness; the other ten mothers denied any disease associated with fever.

摘要

本文呈现了对总共4235名受试者进行血清学检查的结果,这些受试者包括献血者(341人)、孕妇(1784人)、新生儿(833人)、恶性肿瘤患者(248人)、流感样疾病患者(548人)、无菌性脑膜炎患者(295人)、1岁以下脑积水婴儿(40人)、2岁以下患有其他神经系统疾病的婴儿(110人)、脑积水血清学阳性儿童的母亲(12人)以及脑积水血清学阴性儿童的母亲(24人)。调查发现16例血清学确诊的产前淋巴细胞性脉络丛脑膜炎病毒感染病例。在大多数情况下,在儿童中检测到针对该病毒的免疫荧光抗体,其效价较高,而在其母亲中检测到的效价为中度和低度。14名儿童出现脑积水,1名儿童患有婴儿脑瘫,1名儿童患有先天性右侧上睑下垂。在14名患者中发现了脉络膜视网膜变性病灶。在怀孕期间,6名母亲患过流感样疾病;其他10名母亲否认有任何与发热相关的疾病。

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Hydrocephalus due to prenatal infection with the lymphocytic choriomeningitis virus.因产前感染淋巴细胞性脉络丛脑膜炎病毒所致的脑积水。
Infection. 1976;4(4):185-91. doi: 10.1007/BF01638922.
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Acta Virol. 1975 Apr;19(2):165-6.
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