Federspil P
Infection. 1976;4(4):211. doi: 10.1007/BF01638926.
Comparative functional and histological tests were performed in eight groups of ten quinea pigs each, which were administered 50, 75, 100 and 150 mg of netilmicin respecitvely b.i.d. for 29 days, 15 and 25 mg of gentamicin and 50 and 100 mg of amikacin per kg body weight respecitvely b.i.d. and in one control group of ten animals. The tests showed a low degree of ototoxicity and nephrotoxicity of netilmicin.
对八组豚鼠进行了比较功能和组织学测试，每组十只。分别以每日两次、每次50、75、100和150毫克的剂量给豚鼠注射奈替米星，持续29天；以每日两次、每次每千克体重15和25毫克的剂量给豚鼠注射庆大霉素；以每日两次、每次每千克体重50和100毫克的剂量给豚鼠注射阿米卡星。同时设置了一个由十只动物组成的对照组。测试显示奈替米星的耳毒性和肾毒性程度较低。
