Eriksson N E, Ahlstedt S, Belin L
Int Arch Allergy Appl Immunol. 1976;52(1-4):335-46. doi: 10.1159/000231700.
RAST analyses were performed with house dust, animal dander and eleven pollen allergens in 410 adult patients with asthma and/or rhinitis and the findings were compared with skin test and provocation test results. The overall correlation between 1,316 provocation tests and RAST was 78% and the correlation between 1,778 skin tests and RAST was 66%. The relationships between RAST and in vivo tests differed considerably from allergen to allergen. No significant differences were found between various age groups. According to the in vivo tests the RAST showed more often positive results in patients with pronounced allergy than in patients with low-grade allergy. Higher RAST classes were most often combined with positive in vivo tests. It is concluded that in cases with RAST classes 2-4, a reasonably well-established allergy diagnosis can be reached without the inclusion of additional in vivo tests. In other cases, however, application of further diagnostic methods is required.
对410例成年哮喘和/或鼻炎患者进行了针对屋尘、动物皮屑和11种花粉过敏原的放射变应原吸附试验（RAST）分析，并将结果与皮肤试验和激发试验结果进行比较。1316次激发试验与RAST的总体相关性为78%，1778次皮肤试验与RAST的相关性为66%。RAST与体内试验之间的关系因过敏原不同而有很大差异。各年龄组之间未发现显著差异。根据体内试验，RAST在过敏症状明显的患者中比在轻度过敏患者中更常显示阳性结果。较高的RAST分级最常与体内试验阳性结果相关。结论是，在RAST分级为2 - 4级的病例中，无需进行额外的体内试验即可得出合理明确的过敏诊断。然而，在其他情况下，则需要应用进一步的诊断方法。
