Reisin E, Modan M, Habot B, Eliahou H E
Isr J Med Sci. 1976 Nov;12(11):1283-8.
A nomogram for plasma renin activity (PRA), based on 31 normal volunteers, was constructed, and the 95% tolerance limits were computed to the regression line of PRA on 24-h urinary sodium excretion. On this nomogram, reproducibility of the PRA profile for the same patient with essential hypertension was good. Retrospectively, 20 essential hypertension patients with low PRA were matched for age and sex with essential hypertension patients with normal PRA. No statistically significant difference was found between the two groups in either the number of cardiovascular complications or in the blood pressure means. It is concluded that the incidence of cardiovascular complications tends to be similar in all cases of essential hypertension of a similar degree of severity.
基于31名正常志愿者构建了血浆肾素活性（PRA）列线图，并计算了PRA与24小时尿钠排泄回归线的95%容忍限。在该列线图上，原发性高血压同一患者的PRA曲线再现性良好。回顾性研究中，将20例低PRA的原发性高血压患者与年龄和性别相匹配的正常PRA原发性高血压患者进行比较。两组在心血管并发症数量或血压均值方面均未发现统计学显著差异。得出的结论是，在严重程度相似的所有原发性高血压病例中，心血管并发症的发生率往往相似。
