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从患有外阴阴道炎的女性性工作者中分离出的念珠菌属对抗真菌剂和硼酸的敏感性。

Susceptibility of Candida species isolated from female prostitutes with vulvovaginitis to antifungal agents and boric acid.

作者信息

Otero L, Fleites A, Méndez F J, Palacio V, Vázquez F

机构信息

Servicio de Microbiología, Hospital de Cabueñes, Gijón, Spain.

出版信息

Eur J Clin Microbiol Infect Dis. 1999 Jan;18(1):59-61. doi: 10.1007/s100960050227.

Abstract

The aim of this study was to determine the antifungal susceptibility of 108 Candida albicans and 23 Candida glabrata isolates obtained from female prostitutes with vulvovaginitis, a population for which available data is limited. Amphotericin B, flucytosine, and fluconazole were tested by broth microdilution, and boric acid was tested by the agar dilution method. The susceptibility patterns found in this population were the same as those in the general population. Candida glabrata required greater concentrations of boric acid for inhibition in vitro than did Candida albicans.

摘要

本研究的目的是确定从患有外阴阴道炎的女性性工作者中分离出的108株白色念珠菌和23株光滑念珠菌的抗真菌药敏情况,针对这一人群的现有数据有限。采用肉汤微量稀释法检测两性霉素B、氟胞嘧啶和氟康唑,采用琼脂稀释法检测硼酸。该人群中发现的药敏模式与普通人群相同。与白色念珠菌相比,光滑念珠菌在体外抑制需要更高浓度的硼酸。

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