Faniran A O, Peat J K, Woolcock A J
Department of Medicine, University of NSW, St George's Hospital, Kogarah, Australia.
Arch Dis Child. 1998 Nov;79(5):411-4. doi: 10.1136/adc.79.5.411.
The aim of this study was to determine if children in the community with persistent cough can be considered to have asthma. A validated questionnaire was given to the parents of 1245 randomly selected children aged 6-12 years. Atopy was measured with skin prick tests. Children with persistent cough had less morbidity and less atopy compared with children with wheeze. Although the syndrome commonly referred to as "cough variant asthma" could not be shown in this study, a significant number of children with persistent cough had been diagnosed as having asthma and were treated with asthma medications including inhaled corticosteroids. Studies are urgently needed to determine the appropriate treatment for children with persistent cough.
本研究的目的是确定社区中持续咳嗽的儿童是否可被视为患有哮喘。对1245名随机选取的6至12岁儿童的家长发放了一份经过验证的问卷。通过皮肤点刺试验测量特应性。与喘息儿童相比，持续咳嗽的儿童发病率较低且特应性较少。尽管本研究未能证实通常所说的“咳嗽变异性哮喘”综合征，但大量持续咳嗽的儿童已被诊断为患有哮喘，并接受了包括吸入性糖皮质激素在内的哮喘药物治疗。迫切需要开展研究以确定持续咳嗽儿童的恰当治疗方法。
