Frieswijk T A, Smit J P, Rutten W L, Boom H B
Department of Electrical Engineering, University of Twente, Enschede, The Netherlands.
Med Biol Eng Comput. 1998 Jul;36(4):422-30. doi: 10.1007/BF02523209.
Animal experiments and model simulations of monopolar, intrafascicular nerve stimulation are presented to study force-current relationships (recruitment curves). The conductivity of the extraneural medium is of prime importance to the resulting recruitment cures: an insulating extraneural medium generally leads to steeper curves with lower threshold currents than a well-conducting extraneural medium. Extensive statistical comparison of experimental and model results suggests the occurrence of clustering of alpha-motoneurons within the fascicle, manifesting itself mainly by an increased spread in threshold currents, as opposed to the situation where the fibres are distributed uniformly throughout the entire fascicle.
本文介绍了单极、束内神经刺激的动物实验和模型模拟，以研究力-电流关系（募集曲线）。神经外介质的电导率对最终的募集曲线至关重要：与传导良好的神经外介质相比，绝缘的神经外介质通常会导致曲线更陡，阈值电流更低。对实验结果和模型结果进行的广泛统计比较表明，束内α运动神经元存在聚集现象，主要表现为阈值电流的分散性增加，这与纤维均匀分布在整个束中的情况相反。
