Foley K M
Department of Neurology, Memorial Sloan-Kettering Cancer Center and Cornell University Medical College, New York, NY, USA.
Arch Neurol. 1999 Apr;56(4):413-7. doi: 10.1001/archneur.56.4.413.
Advances in cancer pain research and management are an example of the advances that have occurred within the field of neuro-oncology, the medical discipline that includes the diagnosis and treatment of primary central nervous system neoplasms, metastatic and nonmetastatic neurological complications of cancer originating outside the nervous system, and pain associated with cancer. Progress in the diagnosis and treatment of cancer, coupled with advances in our understanding of the anatomy, physiology, pharmacology, and psychology of pain perception, has led to improved care of the patient with pain of malignant origin. Currently, specialized methods of cancer diagnosis and treatment provide the most direct approach to treating cancer pain by treating the cause of the pain. Yet, before the introduction of successful antitumor therapy, when treatment of the cause of the pain has failed or when injury to bone, soft tissue, or nerve has occurred as a result of therapy, appropriate pain management is essential.
癌症疼痛研究与管理方面的进展是神经肿瘤学领域所取得进展的一个例证。神经肿瘤学这一医学学科涵盖原发性中枢神经系统肿瘤的诊断与治疗、起源于神经系统之外的癌症的转移性和非转移性神经并发症，以及与癌症相关的疼痛。癌症诊断与治疗方面的进展，再加上我们对疼痛感知的解剖学、生理学、药理学及心理学理解的进步，已使对恶性起源疼痛患者的护理得到改善。目前，专门的癌症诊断和治疗方法通过治疗疼痛根源提供了治疗癌症疼痛的最直接途径。然而，在成功的抗肿瘤治疗引入之前，当疼痛根源的治疗失败，或者由于治疗导致骨骼、软组织或神经损伤时，恰当的疼痛管理至关重要。
