Hoogerwerf W A, Pasricha P J, Kalloo A N, Schuster M M
The Marvin M. Schuster Center for Digestive and Motility Disorders, Johns Hopkins Bayview Medical Center, Baltimore, Maryland 21224, USA.
Am J Gastroenterol. 1999 Apr;94(4):1029-33. doi: 10.1111/j.1572-0241.1999.01008.x.
Abdominal pain has not been reported generally as a significant feature of the clinical presentation of patients with gastroparesis.
Using a standardized questionnaire, we analyzed the clinical features of 28 consecutive patients referred with established or suspected gastroparesis over a 4-yr period. The diagnosis of gastroparesis was supported by abnormalities in gastric emptying studies (GES), electrogastrography (EGG), or upper endoscopy (EGD). Diagnostic tests were reviewed.
A total of 12 male (mean age 39.5 yr) and 18 female patients (mean age 39.6 yr) were included in this study. These patients had been symptomatic for an average of 37.8 months before their referral to our center. Seven of these patients had insulin-dependent diabetes. Idiopathic gastroparesis was present in more than half of the patients. The symptom profile of the 28 patients was as follows: nausea, 92.9%; abdominal pain, 89.3%; early satiety, 85.7%; and vomiting, 67.9%. The pain was described as burning, vague, or crampy in nature. Only 36% localized to the upper abdomen. In all, 60% of patients complained of postprandial pain, whereas 80% complained of nocturnal pain that interfered with their normal sleeping pattern. In general, pain responded poorly or not at all to prokinetic agents.
Nausea and abdominal pain are the most common complaints of patients with gastroparesis. In 80% of patients, GES and EGG correlated positively.
一般未将腹痛报告为胃轻瘫患者临床表现的显著特征。
我们使用标准化问卷，分析了在4年期间连续转诊的28例确诊或疑似胃轻瘫患者的临床特征。胃轻瘫的诊断通过胃排空研究（GES）、胃电图（EGG）或上消化道内镜检查（EGD）中的异常得到支持。对诊断测试进行了回顾。
本研究共纳入12例男性患者（平均年龄39.5岁）和18例女性患者（平均年龄39.6岁）。这些患者在转诊至我们中心之前平均有症状37.8个月。其中7例患者患有胰岛素依赖型糖尿病。超过一半的患者存在特发性胃轻瘫。28例患者的症状表现如下：恶心，92.9%；腹痛，89.3%；早饱，85.7%；呕吐，67.9%。疼痛性质被描述为烧灼样、模糊不清或痉挛性。仅36%的疼痛局限于上腹部。总体而言，60%的患者主诉餐后疼痛，而80%的患者主诉夜间疼痛，这干扰了他们的正常睡眠模式。一般来说，促动力剂对疼痛的缓解效果不佳或根本无效。
恶心和腹痛是胃轻瘫患者最常见的主诉。80%的患者中，GES和EGG呈正相关。
