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难治性急性闭角型青光眼患者的白内障超声乳化吸除联合房角粘连分离术

Combined phacoemulsification and viscogoniosynechialysis in patients with refractory acute angle-closure glaucoma.

作者信息

Razeghinejad Mohammad Reza

机构信息

Department of Ophthalmology and Poostchi Ophthalmology Research Center, Khalili Hospital, Shiraz Medical University, Shiraz, Iran.

出版信息

J Cataract Refract Surg. 2008 May;34(5):827-30. doi: 10.1016/j.jcrs.2008.01.014.

Abstract

PURPOSE

To evaluate the effectiveness of phacoemulsification and viscogoniosynechialysis in managing refractory acute angle-closure glaucoma (ACG) unresponsive to laser iridotomy and medical therapy.

SETTING

Department of Ophthalmology, Khalili Hospital, Shiraz Medical University, Shiraz, Iran.

METHODS

Eleven patients with acute ACG who did not respond to standard therapy and who had peripheral anterior synechia (PAS) of 270 degrees or less had phacoemulsification and viscogoniosynechialysis. After phacoemulsification, the anterior chamber was deepened with an ophthalmic viscosurgical device, which was then injected near the angle without touching any ocular structure to release the PAS.

RESULTS

Eleven patients with a mean age of 58.9 years were included over a mean follow-up of 7.8 months. Preoperatively, the mean intraocular pressure (IOP) was 39.4 mm Hg and the mean number of antiglaucoma medications, 3.8. Postoperatively, the mean IOP decreased to 13.4 mm Hg (P = .003) and the mean number of medications, to 0.4 (P = .002). The mean logMAR visual acuity improved from 0.94 to 0.55 (P = .007). In 8 eyes (72.8%), IOP was controlled without antiglaucoma therapy. Of patients whose IOP was controlled with medication, 1 was on 3 medications and the others on 1 medication. In all patients except the one whose IOP was controlled by 3 medications, the previously occluded trabecular meshwork was exposed over 360 degrees on gonioscopy.

CONCLUSION

Combined phacoemulsification and viscogoniosynechialysis was an effective and safe treatment for the management of refractory acute ACG that was unresponsive to laser iridotomy and medical therapy.

摘要

目的

评估超声乳化白内障吸除术联合房角粘连分离术治疗对激光虹膜切开术和药物治疗无反应的难治性急性闭角型青光眼(ACG)的有效性。

设置

伊朗设拉子市设拉子医科大学哈利利医院眼科。

方法

11例对标准治疗无反应且周边前粘连(PAS)为270度或以下的急性ACG患者接受了超声乳化白内障吸除术联合房角粘连分离术。超声乳化白内障吸除术后,用眼科粘弹剂加深前房,然后在不接触任何眼结构的情况下将其注入房角附近以松解PAS。

结果

纳入11例平均年龄58.9岁的患者,平均随访7.8个月。术前,平均眼压(IOP)为39.4 mmHg,平均抗青光眼药物数量为3.8种。术后,平均IOP降至13.4 mmHg(P = 0.003),平均药物数量降至0.4种(P = 0.002)。平均对数最小分辨角视力从0.94提高到0.55(P = 0.007)。8只眼(72.8%)无需抗青光眼治疗眼压即得到控制。在眼压通过药物控制的患者中,1例使用3种药物,其他患者使用1种药物。除1例眼压由3种药物控制的患者外,所有患者在房角镜检查中可见先前闭塞的小梁网在360度范围内暴露。

结论

超声乳化白内障吸除术联合房角粘连分离术是治疗对激光虹膜切开术和药物治疗无反应的难治性急性ACG的一种有效且安全的治疗方法。

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