Klink K, Herold B, Bürkmann I
Z Erkr Atmungsorgane. 1976;145(3):322-6.
Parameters of pulmonary mechanics were measured at rest and during physical effort in patients with silicosis and normal subjects. Between normal subjects and patients with silicosis of stage I a significant difference could not be found. However, a decrease of dynamic compliance and an increase of elastic work of breathing were found in patients with silicosis III during exercise. The PT/VT-quotient is already high at rest. These results are not in agreement with the subjective symptom "dyspnea". The feeling of dyspnea appears when the PT/VT-quotient is enhanced signifcantly during exercise in comparison with the value at rest. Therefore, only the PT/VT-quotient is a suitable parameter indicating dyspnea.
在矽肺患者和正常受试者休息时及体力活动期间测量肺力学参数。在正常受试者和I期矽肺患者之间未发现显著差异。然而，III期矽肺患者在运动期间出现动态顺应性降低和呼吸弹性功增加。PT/VT比值在休息时就已经很高。这些结果与主观症状“呼吸困难”不一致。当运动期间PT/VT比值相较于休息时的值显著升高时，会出现呼吸困难的感觉。因此，只有PT/VT比值是指示呼吸困难的合适参数。
