Müller E, Vogel J, Wuthe H, Petro W
Z Erkr Atmungsorgane. 1976 May;145(2):274-83.
Changes in parameters of respiratory mechanics with alteration in breathing frequency, lung volume and physical effort were determined in 23 subjects using automated data collection and data processing. Resistance R, Compliance C and work of breathing W show great dependence on breathing frequency and lung volume. An objective measuring of their changes during exercise requires a constant lung volume and a standardized breathing frequency. Parameters R and C and the maximal pressure amplitude DPM divided by the tidal volume VT show no significant alterations in several degrees of exercise. Work of breathing and work of breathing per tidal volume are enhanced significantly with increasing exercise. These parameters may estimate the mechanics of breathing better than R and C in patients with dyspnea during exercise.
利用自动数据采集和数据处理技术,对23名受试者在呼吸频率、肺容量和体力活动改变时呼吸力学参数的变化进行了测定。阻力R、顺应性C和呼吸功W对呼吸频率和肺容量有很大的依赖性。在运动过程中对其变化进行客观测量需要恒定的肺容量和标准化的呼吸频率。参数R和C以及最大压力振幅DPM除以潮气量VT在几个运动强度下均无显著变化。随着运动强度增加,呼吸功和每潮气量的呼吸功显著增强。在运动时出现呼吸困难的患者中,这些参数可能比R和C能更好地评估呼吸力学。