Pronovost P J, Jenckes M W, Dorman T, Garrett E, Breslow M J, Rosenfeld B A, Lipsett P A, Bass E
Department of Anesthesiology/Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD 21287-7294, USA.
JAMA. 1999 Apr 14;281(14):1310-7. doi: 10.1001/jama.281.14.1310.
Morbidity and mortality rates in intensive care units (ICUs) vary widely among institutions, but whether ICU structure and care processes affect these outcomes is unknown.
To determine whether organizational characteristics of ICUs are related to clinical and economic outcomes for abdominal aortic surgery patients who typically receive care in an ICU.
Observational study, with patient data collected retrospectively and ICU data collected prospectively.
All Maryland hospitals that performed abdominal aortic surgery from 1994 to 1996.
We analyzed hospital discharge data for patients in non-federal acute care hospitals in Maryland who had a principal procedure code for abdominal aortic surgery from January 1994 through December 1996 (n = 2987). We obtained information about ICU organizational characteristics by surveying ICU medical directors at the 46 Maryland hospitals that performed abdominal aortic surgery. Thirty-nine (85%) of the ICU directors completed this survey.
In-hospital mortality and hospital and ICU length of stay.
For patients undergoing abdominal aortic surgery, in-hospital mortality varied among hospitals from 0% to 66%. In multivariate analysis adjusted for patient demographics, comorbid disease, severity of illness, hospital and surgeon volume, and hospital characteristics, not having daily rounds by an ICU physician was associated with a 3-fold increase in in-hospital mortality (odds ratio [OR], 3.0; 95% confidence interval [CI], 1.9-4.9). Furthermore, not having daily rounds by an ICU physician was associated with an increased risk of cardiac arrest (OR, 2.9; 95% CI, 1.2-7.0), acute renal failure (OR, 2.2; 95% CI, 1.3-3.9), septicemia (OR, 1.8; 95% CI, 1.2-2.6), platelet transfusion (OR, 6.4; 95% CI, 3.2-12.4), and reintubation (OR, 2.0; 95% CI, 1.0-4.1). Not having daily rounds by an ICU physician, having an ICU nurse-patient ratio of less than 1:2, not having monthly review of morbidity and mortality, and extubating patients in the operating room were associated with increased resource use.
Organizational characteristics of ICUs are related to differences among hospitals in outcomes of abdominal aortic surgery. Clinicians and hospital leaders should consider the potential impact of ICU organizational characteristics on outcomes of patients having high-risk operations.
重症监护病房(ICU)的发病率和死亡率在不同机构间差异很大,但ICU的结构和护理流程是否会影响这些结果尚不清楚。
确定ICU的组织特征是否与通常在ICU接受治疗的腹主动脉手术患者的临床和经济结果相关。
观察性研究,回顾性收集患者数据,前瞻性收集ICU数据。
1994年至1996年期间在马里兰州进行腹主动脉手术的所有医院。
我们分析了马里兰州非联邦急症护理医院中1994年1月至1996年12月期间主要手术代码为腹主动脉手术患者的出院数据(n = 2987)。我们通过对马里兰州46家进行腹主动脉手术的医院的ICU医疗主任进行调查,获取了有关ICU组织特征的信息。46家ICU主任中有39位(85%)完成了这项调查。
住院死亡率、住院时间和ICU住院时间。
对于接受腹主动脉手术的患者,各医院的住院死亡率在0%至66%之间。在对患者人口统计学、合并症、疾病严重程度、医院和外科医生手术量以及医院特征进行调整的多变量分析中,ICU医生不进行每日查房与住院死亡率增加3倍相关(比值比[OR],3.0;95%置信区间[CI],1.9 - 4.9)。此外,ICU医生不进行每日查房与心脏骤停风险增加相关(OR,2.9;95% CI,1.2 - 7.0)、急性肾衰竭(OR,2.2;95% CI,1.3 - 3.9)、败血症(OR,1.8;95% CI,1.2 - 2.6)、血小板输注(OR,6.4;95% CI,3.2 - 12.4)以及再次插管(OR,2.0;95% CI,1.0 - 4.1)相关。ICU医生不进行每日查房、ICU护士与患者比例小于1:2、不进行每月发病率和死亡率审查以及在手术室为患者拔管与资源使用增加相关。
ICU的组织特征与腹主动脉手术医院间的结果差异相关。临床医生和医院领导应考虑ICU组织特征对高危手术患者结果的潜在影响。