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胶带引起的皮炎中的经表皮水分流失

Transepidermal water loss in adhesive tape induced dermatitis.

作者信息

Hofmann H, Maibach H

出版信息

Contact Dermatitis. 1976 Jun;2(3):171-7. doi: 10.1111/j.1600-0536.1976.tb03019.x.

DOI:10.1111/j.1600-0536.1976.tb03019.x
PMID:1021345
Abstract

As an index of skin barrier function, transepidermal water loss (TEW) was investigated in subjects reactive to adhesive tapes. Tape reactive subjects showed no difference in TEW in untreated skin when compared to non-reactive subjects. Plastic tape and transparent tape produced varying degrees of dermatitis in reactive subjects; the TEW was increased up to 40-fold of the baseline values correlating with the degree of dermatitis. Paper tape and plastic film without adhesive did not produce dermatitis and increased water loss. Regeneration of skin damage was accompanied by a decrease of TEW values. The general problem of tape reactors and tape irritation is discussed.

摘要

作为皮肤屏障功能的指标,对胶带过敏的受试者接受了经表皮水分流失(TEW)检测。与非过敏受试者相比,胶带过敏受试者未经处理的皮肤在TEW方面并无差异。塑料胶带和透明胶带在过敏受试者中引发了不同程度的皮炎;TEW增加至基线值的40倍,且与皮炎程度相关。无粘性的纸带和塑料薄膜未引发皮炎,且水分流失增加。皮肤损伤的修复伴随着TEW值的降低。文中讨论了胶带过敏者和胶带刺激的普遍问题。

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