Crane J M, van den Hof M C, Dodds L, Armson B A, Liston R
Department of Obstetrics and Gynecology, Memorial University of Newfoundland, St. John's, Canada.
Obstet Gynecol. 1999 Apr;93(4):541-4. doi: 10.1016/s0029-7844(98)00480-3.
To identify neonatal complications associated with placenta previa.
This was a population-based, retrospective cohort study involving all singleton deliveries in Nova Scotia from 1988 to 1995. The study group consisted of all completed singleton pregnancies complicated by placenta previa; all other singleton pregnancies were considered controls. Patient information was collected from the Nova Scotia Atlee perinatal database. Neonatal complications were evaluated while controlling for potential confounders. The data were analyzed using chi2, Fisher exact test, and multiple logistic regression.
Among 92,983 pregnancies delivered during the study period, 305 cases of placenta previa were identified (0.33%). After controlling for potential confounders, neonatal complications significantly associated with placenta previa included major congenital anomalies (odds ratio [OR] 2.48), respiratory distress syndrome (OR 4.94), and anemia (OR 2.65). The perinatal mortality rate associated with placenta previa was 2.30% (compared with 0.78% in controls) and was explained by gestational age at delivery, occurrence of congenital anomalies, and maternal age. Although there was a higher rate of preterm births in the placenta previa group (46.56% versus 7.27%), there was no difference in birth weights between groups after controlling for gestational age at delivery.
Neonatal complications of placenta previa included preterm birth, congenital anomalies, respiratory distress syndrome, and anemia. There was no increased occurrence of fetal growth restriction.
确定与前置胎盘相关的新生儿并发症。
这是一项基于人群的回顾性队列研究，纳入了1988年至1995年在新斯科舍省的所有单胎分娩。研究组包括所有因前置胎盘而结束的单胎妊娠；所有其他单胎妊娠被视为对照组。患者信息从新斯科舍省阿特利围产期数据库收集。在控制潜在混杂因素的同时评估新生儿并发症。使用卡方检验、Fisher精确检验和多元逻辑回归分析数据。
在研究期间分娩的92983例妊娠中，确定了305例前置胎盘病例（0.33%）。在控制潜在混杂因素后，与前置胎盘显著相关的新生儿并发症包括重大先天性异常（优势比[OR]2.48）、呼吸窘迫综合征（OR 4.94）和贫血（OR 2.65）。与前置胎盘相关的围产期死亡率为2.30%（对照组为0.78%），这可以通过分娩时的孕周、先天性异常的发生情况和产妇年龄来解释。尽管前置胎盘组的早产率较高（46.56%对7.27%），但在控制分娩时的孕周后，两组之间的出生体重没有差异。
前置胎盘的新生儿并发症包括早产、先天性异常、呼吸窘迫综合征和贫血。胎儿生长受限的发生率没有增加。
