Kon M, Miyamoto Y, Asaoka K, Ishikawa K, Lee H H
Department of Dental Engineering, School of Dentistry, Tokushima University, Japan.
Dent Mater J. 1998 Dec;17(4):223-32. doi: 10.4012/dmj.17.223.
The purpose of this study was to develop an alpha-tricalcium phosphate (alpha-TCP) cement which transforms to hydroxyapatite (HAP) in a relatively short period. We used calcium and phosphate solutions as the liquid phase for the alpha-TCP cement. The alpha-TCP powder was first mixed with CaCl2 solution, and then mixed with NaH2PO4 or Na2HPO3 solution for a total powder/liquid ratio of 1.8. The setting time became shorter with the increase in the concentration of calcium and phosphate solutions, reaching 5 min, whereas the setting time was longer than 30 min when distilled water was used as the liquid phase. X-ray diffraction analysis revealed that the cement was mostly transformed to HAP within 24 h when kept in an incubator. We concluded that alpha-TCP should be mixed with calcium and phosphate solutions since this results in a moderate setting time and fast transformation to HAP even if the method of mixing becomes a little complex.
本研究的目的是开发一种能在相对较短时间内转化为羟基磷灰石（HAP）的α-磷酸三钙（α-TCP）水泥。我们使用钙和磷酸盐溶液作为α-TCP水泥的液相。首先将α-TCP粉末与CaCl2溶液混合，然后与NaH2PO4或Na2HPO3溶液混合，总粉液比为1.8。随着钙和磷酸盐溶液浓度的增加，凝固时间缩短，达到5分钟，而当使用蒸馏水作为液相时，凝固时间超过30分钟。X射线衍射分析表明，该水泥在培养箱中保存24小时内大部分转化为HAP。我们得出结论，α-TCP应与钙和磷酸盐溶液混合，因为即使混合方法略显复杂，这也会导致适中的凝固时间并快速转化为HAP。
