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继发于恶性黑色素瘤的副肿瘤性眼阵挛-肌阵挛

Paraneoplastic opsoclonus-myoclonus secondary to malignant melanoma.

作者信息

Berger J R, Mehari E

机构信息

Department of Neurology, University of Kentucky College of Medicine, Lexington, USA.

出版信息

J Neurooncol. 1999 Jan;41(1):43-5. doi: 10.1023/a:1006189210197.

Abstract

Opsoclonus-myoclonus is a well-described paraneoplastic syndrome that most often occurs in association with small cell carcinoma of the lung and breast carcinoma. To the best of our knowledge, we describe the first reported case of paraneoplastic opsoclonus-myoclonus occurring is association with malignant melanoma. Antineuronal antibodies were not identified despite repeated testing. No therapeutic benefit was observed following corticosteroid administration.

摘要

眼阵挛-肌阵挛是一种已被充分描述的副肿瘤综合征,最常与肺癌和乳腺癌中的小细胞癌相关。据我们所知,我们描述了首例与恶性黑色素瘤相关的副肿瘤性眼阵挛-肌阵挛病例。尽管进行了反复检测,但未发现抗神经元抗体。给予皮质类固醇后未观察到治疗效果。

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