Lewis Mark A, Hartmann Lynn C, Lachance Daniel H, Jimenez Rafael E
Department of Oncology;
Rare Tumors. 2010 Sep 30;2(3):e42. doi: 10.4081/rt.2010.e42.
Paraneoplastic opsoclonus is well described in neuroblastoma. In the adult oncologic population, opsoclonus is seen usually within the context of opsoclonus-myoclonus ataxia and is associated most strongly with small-cell lung cancer. Patients with paraneoplastic opsoclonus are often seronegative. Patients with gynecologic malignancies are known to be predisposed to paraneoplastic syndromes; however, we describe the first case of paraneoplastic opsoclonus in association with endometrial cancer.
副肿瘤性眼阵挛在神经母细胞瘤中已有详细描述。在成人肿瘤患者群体中，眼阵挛通常见于眼阵挛-肌阵挛共济失调的背景下，且与小细胞肺癌的关联最为密切。副肿瘤性眼阵挛患者通常血清学呈阴性。已知妇科恶性肿瘤患者易患副肿瘤综合征；然而，我们描述了首例与子宫内膜癌相关的副肿瘤性眼阵挛病例。
