Wysocki A, Beben P, Winiarski M
II Katedry i Klinika Chirurgii Ogólnej Collegium Medicum, Uniwersytetu Jagiellońskiego w Krakowie.
Przegl Lek. 1998;55(10):508-11.
The serum iron level drops in many diseases and after bone fractures or elective surgical operations. The aim of this study was to determine if the degree of stress hypoferremia depends on severity of the operation. Serum iron concentration and TIBC was measured during two weeks in 37 patients. The first group consisted of 29 patients operated for ingunal hernia or cholelithiasis. It was laparoscopic cholecystectomy or classical or laparoscopic hernia repair. These types of operations were considered as mild surgical stress. The second group consisted of 8 patients with colon cancer, who had segmental colon resection. This operation was considered as severe surgical stress. The patients with colon cancer had significantly lower preoperative serum iron level. After operations, profound but temporal drop in serum iron concentration was observed in both groups of patients. TIBC drops but not so significantly. The diagrams illustrating changes of iron concentration after operations looked similar in both groups.
The changes of iron concentration after abdominal operations are independent of the severity of surgical stress.
许多疾病以及骨折或择期手术后血清铁水平会下降。本研究的目的是确定应激性低铁血症的程度是否取决于手术的严重程度。对37例患者在两周内测量了血清铁浓度和总铁结合力(TIBC)。第一组由29例因腹股沟疝或胆结石接受手术的患者组成。手术方式为腹腔镜胆囊切除术或经典或腹腔镜疝修补术。这些类型的手术被视为轻度手术应激。第二组由8例结肠癌患者组成,他们接受了结肠部分切除术。该手术被视为重度手术应激。结肠癌患者术前血清铁水平显著较低。术后,两组患者均观察到血清铁浓度显著但短暂下降。TIBC下降但不明显。两组术后铁浓度变化的图表看起来相似。
腹部手术后铁浓度的变化与手术应激的严重程度无关。