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Prevention of premature birth.预防早产。
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2
Chlamydia trachomatis detected in human placenta.在人胎盘中检测到沙眼衣原体。
J Clin Pathol. 1997 Oct;50(10):852-5. doi: 10.1136/jcp.50.10.852.
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Chlamydial antibodies in women who suffer miscarriage.流产女性体内的衣原体抗体。
Br J Obstet Gynaecol. 1996 Feb;103(2):137-41. doi: 10.1111/j.1471-0528.1996.tb09665.x.
4
Protective efficacy of a parenterally administered MOMP-derived synthetic oligopeptide vaccine in a murine model of Chlamydia trachomatis genital tract infection: serum neutralizing IgG antibodies do not protect against chlamydial genital tract infection.经肠胃外给药的主要外膜蛋白（MOMP）衍生合成寡肽疫苗在沙眼衣原体生殖道感染小鼠模型中的保护效力：血清中和性IgG抗体不能预防衣原体生殖道感染。
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Intravaginal inoculation of mice with the Chlamydia trachomatis mouse pneumonitis biovar results in infertility.用沙眼衣原体小鼠肺炎生物变种对小鼠进行阴道内接种会导致不育。
Infect Immun. 1994 May;62(5):2094-7. doi: 10.1128/iai.62.5.2094-2097.1994.
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Chlamydial serologic studies and recurrent spontaneous abortion.衣原体血清学研究与复发性自然流产
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Protection against infertility in a BALB/c mouse salpingitis model by intranasal immunization with the mouse pneumonitis biovar of Chlamydia trachomatis.通过用沙眼衣原体小鼠肺炎生物变种进行鼻内免疫在BALB/c小鼠输卵管炎模型中预防不孕
Infect Immun. 1994 Aug;62(8):3354-62. doi: 10.1128/iai.62.8.3354-3362.1994.
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Neonatal mortality rate: is further improvement possible?新生儿死亡率：还有进一步改善的可能吗？
J Pediatr. 1995 Mar;126(3):427-33. doi: 10.1016/s0022-3476(95)70463-9.
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Serologic evidence of Chlamydia trachomatis infection and risk of preterm birth.沙眼衣原体感染的血清学证据与早产风险
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Association between bacterial vaginosis and preterm delivery of a low-birth-weight infant. The Vaginal Infections and Prematurity Study Group.细菌性阴道病与低体重儿早产之间的关联。阴道感染与早产研究组。
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一种用于研究孕期沙眼衣原体生殖道感染的小鼠模型。

A murine model for the study of Chlamydia trachomatis genital infections during pregnancy.

作者信息

Pal S, Peterson E M, De La Maza L M

机构信息

Department of Pathology, University of California, Irvine, Irvine, California 92697-4800, USA.

出版信息

Infect Immun. 1999 May;67(5):2607-10. doi: 10.1128/IAI.67.5.2607-2610.1999.

DOI:10.1128/IAI.67.5.2607-2610.1999
PMID:10225927
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC116010/
Abstract

Pregnant BALB/c mice were inoculated intravaginally on day 5 of gestation with the Chlamydia trachomatis mouse pneumonitis biovar. Animals that received 10(5), 10(6), or 10(7) inclusion-forming units (IFU) of C. trachomatis delivered prematurely on days 15 to 16 of gestation. A focal inflammatory infiltrate was observed in the wall of the uterus on the day 14 of gestation in animals inoculated with 10(5) IFU. In this group of mice, immunohistochemical analysis showed chlamydial inclusions in the endometrium and fetal membranes.

摘要

妊娠第5天，将沙眼衣原体小鼠肺炎生物变种经阴道接种于怀孕的BALB/c小鼠。接种10⁵、10⁶或10⁷个沙眼衣原体包涵体形成单位（IFU）的动物在妊娠第15至16天早产。接种10⁵ IFU的动物在妊娠第14天，子宫壁出现局灶性炎性浸润。在这组小鼠中，免疫组化分析显示子宫内膜和胎膜中有衣原体包涵体。