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目标呼吸困难评分可预测预期耗氧量以及目标心率值。

Target dyspnea ratings predict expected oxygen consumption as well as target heart rate values.

作者信息

Mejia R, Ward J, Lentine T, Mahler D A

机构信息

Section of Pulmonary and Critical Care Medicine, Department of Medicine, Dartmouth Medical School, Lebanon, New Hampshire, USA.

出版信息

Am J Respir Crit Care Med. 1999 May;159(5 Pt 1):1485-9. doi: 10.1164/ajrccm.159.5.9810039.

Abstract

A target heart rate (THR) is the traditional method to prescribe and monitor exercise training intensity in healthy individuals. However, patients with chronic obstructive pulmonary disease (COPD) are limited by ventilatory impairment and dyspnea rather than cardiovascular factors. An alternative approach is to use dyspnea ratings as a target for exercise training in patients with respiratory disease just as ratings of perceived exertion have been used in healthy individuals. The study was a randomized, parallel group trial comparing the ability of patients with COPD to accurately and reliably produce an exercise intensity using a target dyspnea rating (TDR) versus a THR. At Visit 1 patients performed an incremental exercise test on the cycle ergometer, and target values were calculated at approximately 75% of maximal oxygen consumption (V O2). At Visits 2 (3 to 5 d later) and 3 (2 wk later) each patient was instructed to produce a TDR or a THR for 10 min of submaximal exertion. Anthropometric characteristics, lung function, and exercise performance were similar for the 22 patients in each group at Visit 1. For the TDR group the dyspnea target was 2.5 +/- 1.5 at an expected V O2 of 0.88 +/- 0.28 L/min; for the THR group the heart rate (HR) target was 114 +/- 15 beats/min at an expected V O2 of 0.76 +/- 0.29 L/min (p = 0.18 for V O2 between groups). Compared with the expected V O2 from Visit 1, the individual percent differences in V O2 at Visit 2 were -3.9 +/- 18.1% (TDR) and -0.5 +/- 23.2% (THR) (p = 0.58); at Visit 3 the individual percent differences in V O2 were -2.3 +/- 17.0% (TDR) and 2.6 +/- 30.6% (THR) (p = 0.52). The number of patients < 10% and >/= 10% of the expected V O2 were similar for the two groups at Visits 2 (p = 0.38) and 3 (p = 0.27). There were no significant differences for V O2 values (absolute or individual percent) at Visits 2 and 3 for each group and between the groups (p = 0.79). In conclusion, patients with symptomatic COPD demonstrated a comparable ability to use dyspnea ratings and HR as a target to accurately and reliably produce an expected exercise intensity (approximately 75% of V O2max) for 10 min of submaximal exertion.

摘要

目标心率(THR)是为健康个体规定和监测运动训练强度的传统方法。然而,慢性阻塞性肺疾病(COPD)患者受到通气功能障碍和呼吸困难的限制,而非心血管因素。另一种方法是将呼吸困难分级用作呼吸系统疾病患者运动训练的目标,就像在健康个体中使用自觉用力分级一样。该研究是一项随机平行组试验,比较了COPD患者使用目标呼吸困难分级(TDR)与目标心率(THR)准确且可靠地产生运动强度的能力。在第1次就诊时,患者在自行车测力计上进行递增运动试验,并在最大耗氧量(V O2)的约75%时计算目标值。在第2次就诊(3至5天后)和第3次就诊(2周后),指示每位患者在次最大用力状态下持续10分钟,以达到TDR或THR。每组的22名患者在第1次就诊时的人体测量特征、肺功能和运动表现相似。对于TDR组,在预期V O2为0.88±0.28升/分钟时,呼吸困难目标为2.5±1.5;对于THR组,在预期V O2为0.76±0.29升/分钟时,心率(HR)目标为114±15次/分钟(两组间V O2的p值为0.18)。与第1次就诊时的预期V O2相比,第2次就诊时V O2的个体百分比差异在TDR组为-3.9±18.1%,在THR组为-0.5±23.2%(p = 0.58);在第3次就诊时,V O2的个体百分比差异在TDR组为-2.3±17.0%,在THR组为2.6±30.6%(p = 0.52)。在第2次就诊(p = 0.38)和第3次就诊(p = 0.27)时,两组中V O2低于预期值10%和高于或等于预期值10%的患者数量相似。每组在第2次和第3次就诊时以及两组之间的V O2值(绝对值或个体百分比)均无显著差异(p = 0.79)。总之,有症状的COPD患者在使用呼吸困难分级和心率作为目标以准确且可靠地产生预期运动强度(约为V O2max的75%)进行10分钟次最大用力运动方面表现出相当的能力。

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