烟草细胞系中的瞬时环己酰亚胺抗性
Transient cycloheximide resistance in a tobacco cell line.
作者信息
Maliga P, Lázár G, Sváb Z, Nagy F
出版信息
Mol Gen Genet. 1976 Dec 22;149(3):267-71. doi: 10.1007/BF00268527.
PMID:1023042
Abstract
Cylcoheximide-resistant cell lines have been recovered from tissue cultures of haploid Nicotiana tabacum at the usual mutant frequency (10(-6)). One such line, CR 4/6 was studied in detail. Resistance is based on the potential of the callus to inactive cycloheximide. The transient nature of the resistance and its association with differentiated cells indicate that the new phenotype is not due to a mutation, but rather to an alteration in gene expression.
摘要
已从单倍体烟草的组织培养物中以通常的突变频率（10^(-6)）获得了抗放线菌酮的细胞系。对其中一个这样的细胞系CR 4/6进行了详细研究。抗性基于愈伤组织使放线菌酮失活的能力。抗性的短暂性质及其与分化细胞的关联表明，新表型不是由于突变，而是由于基因表达的改变。
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