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PLoS One. 2016 May 19;11(5):e0154560. doi: 10.1371/journal.pone.0154560. eCollection 2016.
2
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Surv Ophthalmol. 2014 Nov-Dec;59(6):627-35. doi: 10.1016/j.survophthal.2014.06.002. Epub 2014 Jun 18.
3
Disease manifestations and pathogenic mechanisms of Group A Streptococcus.A 组链球菌的疾病表现及致病机制
Clin Microbiol Rev. 2014 Apr;27(2):264-301. doi: 10.1128/CMR.00101-13.
4
Severe acute endogenous endophthalmitis with Staphylococcus epidermidis in a systemically well patient.一名全身状况良好的患者发生了由表皮葡萄球菌引起的严重急性内源性眼内炎。
Ophthalmol Eye Dis. 2011 Oct 19;3:25-8. doi: 10.4137/OED.S5883. Print 2011.
5
Hypervirulent (hypermucoviscous) Klebsiella pneumoniae: a new and dangerous breed.高毒力(高黏液性)肺炎克雷伯菌:一种新型且危险的病原体。
Virulence. 2013 Feb 15;4(2):107-18. doi: 10.4161/viru.22718. Epub 2013 Jan 9.
6
The diabetic ocular environment facilitates the development of endogenous bacterial endophthalmitis.糖尿病患者的眼部环境有利于内源性细菌眼内炎的发生。
Invest Ophthalmol Vis Sci. 2012 Nov 1;53(12):7426-31. doi: 10.1167/iovs.12-10661.
7
Endogenous bacterial endophthalmitis: a 17-year prospective series and review of 267 reported cases.内源性细菌性眼内炎:一项为期17年的前瞻性研究及对267例报告病例的综述
Surv Ophthalmol. 2003 Jul-Aug;48(4):403-23. doi: 10.1016/s0039-6257(03)00054-7.
8
Endogenous endophthalmitis: an 18-year review of culture-positive cases at a tertiary care center.内源性眼内炎:一家三级医疗中心18年培养阳性病例回顾。
Medicine (Baltimore). 2003 Mar;82(2):97-105. doi: 10.1097/00005792-200303000-00004.
9
Endogenous Aspergillus endophthalmitis occurring in a child with normal immune function.免疫功能正常的儿童发生内源性曲霉性眼内炎。
Eye (Lond). 2000 Aug;14 ( Pt 4):670-1. doi: 10.1038/eye.2000.169.
10
Endogenous Pseudomonas endophthalmitis in an immunocompetent patient: a case for early diagnosis and treatment.免疫功能正常患者的内源性铜绿假单胞菌眼内炎:早期诊断与治疗的病例报告
Eye (Lond). 2000 Apr;14 ( Pt 2):253-4. doi: 10.1038/eye.2000.69.

一名42岁健康男性的内源性A组链球菌性眼内炎:病例报告

Endogenous Group A Streptococcal Endophthalmitis in a Healthy 42-Year-Old Man: A Case Report.

作者信息

Duong Tan, Shahbazi Shahin, Lee Sung

机构信息

Internal Medicine Resident at Broward Health Medical Center in Fort Lauderdale, FL.

Internist in the Department of Hospital Medicine at the South Sacramento Medical Center in CA.

出版信息

Perm J. 2018;22:17-081. doi: 10.7812/TPP/17-081.

DOI:10.7812/TPP/17-081
PMID:30005734
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6045508/
Abstract

INTRODUCTION

Endogenous endophthalmitis is a rare condition that is caused by hematogenous spread of bacteria or fungi and is usually seen in patients with predisposed medical conditions. We are reporting an unusual case of group A streptococcal infection causing endogenous endophthalmitis and septic arthritis in a healthy 42-year-old man.

CASE PRESENTATION

A previously healthy 42-year-old man presented to the Emergency Department with chills, fever, left wrist pain, left eye pain, and vision loss. Owing to the acute onset of the septic arthritis and the patient's bandemia, the Ophthalmology Department was consulted for suspicion of endophthalmitis. Blood cultures, left wrist synovial fluid cultures, and vitreous cultures grew group A streptococcus. An incision and drainage of the left wrist was performed, and intravitreal injection of vancomycin was given. The patient's vision was responsive only to light on discharge from the hospital. The patient underwent a left eye evisceration 2 months later.

DISCUSSION

Endophthalmitis provides a difficult diagnostic and therapeutic challenge. However, even with prompt treatment, visual outcomes may be poor.

摘要

引言

内源性眼内炎是一种罕见的病症,由细菌或真菌的血行播散引起,通常见于有易感基础疾病的患者。我们报告一例不寻常的A组链球菌感染病例,该感染导致一名42岁健康男性发生内源性眼内炎和化脓性关节炎。

病例介绍

一名既往健康的42岁男性因寒战、发热、左手腕疼痛、左眼疼痛和视力丧失就诊于急诊科。由于化脓性关节炎急性起病且患者出现杆状菌血症,眼科会诊怀疑眼内炎。血培养、左手腕滑液培养和玻璃体培养均培养出A组链球菌。对左手腕进行了切开引流,并给予玻璃体内注射万古霉素。患者出院时视力仅对光有反应。2个月后患者接受了左眼眼球摘除术。

讨论

眼内炎在诊断和治疗方面都具有挑战性。然而,即使及时治疗,视力预后可能也很差。