Shults R A, Arndt V, Olshan A F, Martin C F, Royce R A
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, USA.
Epidemiology. 1999 May;10(3):250-4.
We examined the effects of short interpregnancy intervals on small-for-gestational age and preterm births in a biracial population using North Carolina birth certificate data from 1988 to 1994. We defined small-for-gestational age birth as being below the 10th percentile on a race-, sex-, and parity-specific growth curve after a gestation of 37-42 weeks. We defined preterm birth as a gestation of less than 37 weeks. We analyzed birth records from all eligible singleton births to black or white women ages 15-45 years after an interpregnancy interval of 0-3 months (N = 11,451) and a random sample of singleton births after an interval of 4-24 months (N = 23,118). We defined interpregnancy interval exposure categories as 0-3, 4-12, and 13-24 months. The multivariate adjusted odds ratio for small-for-gestational age births after interpregnancy intervals of 0-3 months compared with 13-24-month intervals was 1.6 (95% confidence interval = 1.4-1.8). The odds ratio for preterm birth after interpregnancy intervals of 0-3 months was 1.2 (95% confidence interval = 1.1-1.3). Odds ratios did not vary substantially by race for either outcome.
我们利用北卡罗来纳州1988年至1994年的出生证明数据，研究了短生育间隔对不同种族人群中小于胎龄儿和早产的影响。我们将小于胎龄儿出生定义为在孕37 - 42周后，根据种族、性别和胎次特异性生长曲线处于第10百分位数以下。我们将早产定义为孕周小于37周。我们分析了所有符合条件的15 - 45岁黑人或白人女性单胎分娩的记录，这些女性的生育间隔为0 - 3个月（N = 11,451），以及生育间隔为4 - 24个月的单胎分娩随机样本（N = 23,118）。我们将生育间隔暴露类别定义为0 - 3个月、4 - 12个月和13 - 24个月。与13 - 24个月的生育间隔相比，0 - 3个月生育间隔后小于胎龄儿出生的多变量调整比值比为1.6（95%置信区间 = 1.4 - 1.8）。0 - 3个月生育间隔后早产的比值比为1.2（95%置信区间 = 1.1 - 1.3）。两种结局的比值比在不同种族间均无显著差异。
