Dean Sohni V, Lassi Zohra S, Imam Ayesha M, Bhutta Zulfiqar A
Reprod Health. 2014 Sep 26;11 Suppl 3(Suppl 3):S2. doi: 10.1186/1742-4755-11-S3-S2.
Preconception care recognizes that many adolescent girls and young women will be thrust into motherhood without the knowledge, skills or support they need. Sixty million adolescents give birth each year worldwide, even though pregnancy in adolescence has mortality rates at least twice as high as pregnancy in women aged 20-29 years. Reproductive planning and contraceptive use can prevent unintended pregnancies, unsafe abortions and sexually-transmitted infections in adolescent girls and women. Smaller families also mean better nutrition and development opportunities, yet 222 million couples continue to lack access to modern contraception.
A systematic review and meta-analysis of the evidence was conducted to ascertain the possible impact of preconception care for adolescents, women and couples of reproductive age on MNCH outcomes. A comprehensive strategy was used to search electronic reference libraries, and both observational and clinical controlled trials were included. Cross-referencing and a separate search strategy for each preconception risk and intervention ensured wider study capture.
Comprehensive interventions can prevent first pregnancy in adolescence by 15% and repeat adolescent pregnancy by 37%. Such interventions should address underlying social and community factors, include sexual and reproductive health services, contraceptive provision; personal development programs and emphasizes completion of education. Appropriate birth spacing (18-24 months from birth to next pregnancy compared to short intervals <6 months) can significantly lower maternal mortality, preterm births, stillbirths, low birth weight and early neonatal deaths.
Improving adolescent health and preventing adolescent pregnancy; and promotion of birth spacing through increasing correct and consistent use of effective contraception are fundamental to preconception care. Promoting reproductive planning on a wider scale is closely interlinked with the reliable provision of effective contraception, however, innovative strategies will need to be devised, or existing strategies such as community-based health workers and peer educators may be expanded, to encourage girls and women to plan their families.
孕前保健认识到,许多青春期女孩和年轻女性在没有所需知识、技能或支持的情况下就会成为母亲。尽管全球每年有6000万青少年分娩,而青少年怀孕的死亡率至少是20至29岁女性怀孕死亡率的两倍。生殖规划和避孕措施的使用可以预防青春期女孩和女性意外怀孕、不安全流产和性传播感染。家庭规模较小也意味着更好的营养和发展机会,但仍有2.22亿对夫妇无法获得现代避孕措施。
对证据进行系统综述和荟萃分析,以确定孕前保健对青少年、育龄妇女和夫妇的孕产妇和儿童健康结局可能产生的影响。采用综合策略检索电子参考文献库,纳入观察性和临床对照试验。交叉引用以及针对每种孕前风险和干预措施的单独检索策略确保了更广泛的研究覆盖范围。
综合干预措施可将青少年首次怀孕率降低15%,青少年再次怀孕率降低37%。此类干预措施应解决潜在的社会和社区因素,包括性健康和生殖健康服务、避孕措施提供、个人发展项目,并强调完成教育。适当的生育间隔(从分娩到下次怀孕间隔18至24个月,而不是短于6个月的间隔)可显著降低孕产妇死亡率、早产、死产、低出生体重和早期新生儿死亡。
改善青少年健康和预防青少年怀孕;通过增加正确和持续使用有效避孕措施来促进生育间隔,是孕前保健的基础。在更广泛范围内促进生殖规划与可靠提供有效避孕措施密切相关,然而,需要制定创新策略,或者扩大基于社区的卫生工作者和同伴教育者等现有策略,以鼓励女孩和妇女规划家庭。