Loftus C M
Department of Neurosurgery, University of Oklahoma College of Medicine, Oklahoma City, USA.
Neurol Med Chir (Tokyo). 1998;38 Suppl:268-74. doi: 10.2176/nmc.38.suppl_268.
Four randomized cooperative trials for asymptomatic carotid artery disease and three randomized cooperative trials of symptomatic carotid artery disease have been completed and published. There are now firm and proven indications for carotid artery reconstruction. Asymptomatic carotid artery disease with 60% or greater linear stenosis on angiography has been shown to be better treated with surgery than with medical therapy alone. For symptomatic patients, linear stenoses of 50% of greater have been shown to have a significant benefit with surgical treatment. All surgical recommendations are based on a morbidity/mortality of 3% or less for the individual surgeon.
四项关于无症状颈动脉疾病的随机合作试验以及三项关于有症状颈动脉疾病的随机合作试验已经完成并发表。目前，颈动脉重建有了确切且已得到证实的指征。血管造影显示线性狭窄达60%或更高的无症状颈动脉疾病，手术治疗比单纯药物治疗效果更好。对于有症状的患者，线性狭窄达50%或更高时，手术治疗已显示出显著益处。所有手术建议均基于个体外科医生3%或更低的发病率/死亡率。
