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单核细胞检测对过敏性支气管哮喘诊断的评估(作者译)

[Evaluation of the monocyte test for diagnosis of allergic asthma bronchiale (author's transl)].

作者信息

Zochert J, Schröder K J, Zochert G

出版信息

Z Erkr Atmungsorgane. 1976 Sep;146(3):311-7.

PMID:1023533
Abstract

We investigated, if in routine work the relative simple monocyte test can improve the diagnostic yield of allergic asthma bronchiale in comparison with the inhalative allergen test. In 600 patients differential counts in peripheral blood were performed before, 30, and 60 minutes after inhalation of the allergen and the increase of monocytes was evaluated. Monocyte test and inhalative allergen test proved to be concordant in 67%, this value was statistically significant, but control trials failed in 11%. Therefore, the monocyte test fails to be of diagnostic value in allergic asthma, it does not increase additionally the diagnostic yield as a routine method.

摘要

我们研究了在日常工作中,相对简单的单核细胞检测与吸入性过敏原检测相比,是否能提高过敏性支气管哮喘的诊断率。对600名患者在吸入过敏原前、吸入后30分钟和60分钟进行外周血分类计数,并评估单核细胞的增加情况。单核细胞检测与吸入性过敏原检测的结果在67%的病例中是一致的,该值具有统计学意义,但有11%的对照试验未成功。因此,单核细胞检测在过敏性哮喘中没有诊断价值,作为一种常规方法,它并不能额外提高诊断率。

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