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[抗淋巴细胞血清对辐射嵌合体脾脏造血恢复早期阶段的刺激作用]

[Stimulant effect of antilymphocytic serum on early stages of hematopoietic recovery in the spleen of radiation chimeras].

作者信息

Zaĭtseva K K, Nezdatnyĭ M M

出版信息

Biull Eksp Biol Med. 1976 Dec;82(12):1457-9.

PMID:1023975
Abstract

Experiments conducted on 236 BALB/c mice were aimed at the study of the effect of the antilymphocytic serum on the hemopoiesis recovery in the spleen of the radiation chimeras, since the antilymphocytic serum was known to increase the number of macroscopic hemopoietic colonies. This increase was found to be due to the intensification of the first hemopoietic recovery stage, i.e. to the acceleration and intensification of the reticular cell activation in the recepient's spleen.

摘要

对236只BALB/c小鼠进行的实验旨在研究抗淋巴细胞血清对辐射嵌合体脾脏造血恢复的影响,因为已知抗淋巴细胞血清会增加宏观造血集落的数量。发现这种增加是由于造血恢复第一阶段的强化,即受体脾脏中网状细胞激活的加速和强化。

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