Bogoslovskaia S I
Farmakol Toksikol. 1976 Nov-Dec;39(6):693-6.
Experiments set up on rabbits showed that with their intravenous administration in a dose of 10 mg/kg antiphein, aethimizol, allilnorantipheins and propylnorantiphein catalize the activity of the pentosophosphate mode of the carbohydrates transformation. The character of the action and the intensity of the effect depend on the features distinguishing the chemical structure of the substances, of particular importance here being changed conformation of the molecule.
在兔子身上进行的实验表明,以10毫克/千克的剂量静脉注射安替芬、乙硫咪唑、烯丙基去甲安替芬和丙基去甲安替芬时,它们会催化碳水化合物转化的戊糖磷酸途径的活性。作用的性质和效果的强度取决于区分这些物质化学结构的特征,在这里分子构象的变化尤为重要。