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恒河猴红核橄榄束的放射自显影研究。

An autoradiographic study of the rubroolivary tract in the rhesus monkey.

作者信息

Strominger N L, Truscott T C, Miller R A, Royce G J

出版信息

J Comp Neurol. 1979 Jan 1;183(1):33-45. doi: 10.1002/cne.901830104.

DOI:10.1002/cne.901830104
PMID:102667
Abstract

Autoradiographic tracing methods were employed to study the course and distribution of the rubroolivary tract following unilateral injections of tritiated leucine into the rostral red nucleus of seven rhesus monkeys. A topographic organization of projections to the ipsilateral principal nucleus of the inferior olivary complex was demonstrated. Lateral and medial portions of the rostral red nucleus projected to medial parts of the dorsal and ventral laminae of the principal inferior olive respectively; neurons in intermediate lateralities emitted fibers which terminated in lateral parts of the principal olive. Injections involving the oral end of the rostral red nucleus elicited label overlying the medial accessory olive in addition to the principal nucleus. Projections to the medial accessory olive may have arisen from the rostral end of the red nucleus and/or the immediately adjacent tegmentum. There were no projections to the dorsal accessory olive. Fibers of rubral origin also were distributed ipsilaterally to several reticular nuclei including the pedunculopontine, pontis oralis, caudalis, and gigantocellularis.

摘要

采用放射自显影追踪方法,对7只恒河猴的延髓红核单侧注射氚标记亮氨酸后,研究红核橄榄束的走行和分布。结果显示了向下橄榄复合体同侧主核投射的拓扑结构。延髓红核的外侧和内侧部分分别投射到下橄榄主核背侧和腹侧叶的内侧部分;中间部位的神经元发出的纤维终止于下橄榄主核的外侧部分。涉及延髓红核嘴侧端的注射除了在下橄榄主核上引起标记外,还在上橄榄内侧核上出现标记。向上橄榄内侧核的投射可能起源于红核的嘴侧端和/或紧邻的被盖。没有发现投射到上橄榄背侧核的情况。红核起源的纤维也同侧分布到几个网状核,包括脚桥核、脑桥嘴侧核、尾侧核和巨细胞网状核。

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