Polak L
Immunology. 1976 Sep;31(3):425-32.
Lymph nodes--and to a lesser extent spleen cells--from guinea-pigs tolerant to DNCB contact sensitivity, when injected into normal syngeneic guinea-pigs, decrease the ability of the recipients to become sensitized to contact with DNCB. The difference between the complete tolerance transferred by parabiosis with tolerant partners and the partial tolerance induced by transfer of tolerant cells can be explained by the different numbers of cells homing in the recipients. The tolergen does not play any role in the transfer of tolerance.
对二硝基氯苯(DNCB)接触敏感性产生耐受的豚鼠的淋巴结——以及程度稍轻的脾细胞——当注入同基因正常豚鼠体内时,会降低受体对接触DNCB产生致敏的能力。通过与耐受伙伴联体共生所传递的完全耐受与通过转移耐受细胞所诱导的部分耐受之间的差异,可以用归巢到受体中的细胞数量不同来解释。耐受原在耐受性转移中不发挥任何作用。