Schwarzberg H, Hartmann G, Kovács G L, Telegdy G
Acta Physiol Acad Sci Hung. 1976;47(2-3):127-31.
Oxytocin (500 mu u) and vasopressin (50 mu u) were injected into the lateral ventricle and its effect on hypothalamic self-stimulation has been studied. Oxytocin increased, while vasopressin decreased the self-stimulation rate tested 10-20 min following application. The hypothalamic and mesencephalic serotonin content decreased slightly while plasma corticosterone content did not change 20 min after oxytocin and vasopressin administration compared to the injected control animals. The data suggest that vasopressin and oxytocin have an opposite effect on self-stimulation and this action is not mediated through the brain serotoninergic or pituitary-adrenocortical axis.
将500毫微单位的催产素和50毫微单位的加压素注入侧脑室，并研究了其对下丘脑自我刺激的影响。催产素可提高自我刺激率，而加压素则使其在给药后10 - 20分钟测试时降低。与注射对照动物相比，在给予催产素和加压素20分钟后，下丘脑和中脑的血清素含量略有下降，而血浆皮质酮含量未发生变化。数据表明，加压素和催产素对自我刺激具有相反的作用，且这种作用不是通过脑血清素能系统或垂体 - 肾上腺皮质轴介导的。
