Chasey D, Cartwright S F
Res Vet Sci. 1978 Sep;25(2):255-6. doi: 10.1016/S0034-5288(18)32994-1.
Porcine epidemic diarrhoea type II was reproduced in experimental pigs of various ages by oral dosing with minced intestine from a naturally occurring case of the disease. Virus-like particles which probably represent an unidentified coronavirus were seen by electron microscopy in the faeces and intestinal epithelium of infected animals.
通过给不同年龄的实验猪口服取自自然发病病例的切碎肠道组织,成功复制出了II型猪流行性腹泻。通过电子显微镜观察发现,受感染动物的粪便和肠道上皮细胞中存在可能代表一种未鉴定冠状病毒的病毒样颗粒。