Loviselli A, Solinas V M, Mameli E G, Lixi F M, Cirillo R, Velluzi F, Calò M C, Vona G
Institute of Internal Medicine, University of Cagliari, Italy.
Anthropol Anz. 1999 Mar;57(1):25-32.
The distributions of some genetic markers in 106 Sardinian individuals with insulin-dependent diabetes mellitus (IDDM) and in a control sample of 186 nondiabetic Sardinians were studied. A strong association of IDDM with some phenotypes of ACP, PGM1, C3 and GC genetic markers was found. In the IDDM patients there is a significant increase of ACP B, ACP B-C, PGM1 1S-1F and GC 1S-2 phenotypes. Particularly the individuals with the ACP B, PGM1 1S-1F and GC 1S-2 phenotypes show the highest values of the relative risk (RR) and the attributable risk (AR) and seem to be more susceptible to IDDM disease.
对106名患有胰岛素依赖型糖尿病（IDDM）的撒丁岛人和186名非糖尿病撒丁岛人组成的对照样本中的一些遗传标记分布进行了研究。发现IDDM与ACP、PGM1、C3和GC遗传标记的某些表型之间存在强关联。在IDDM患者中，ACP B、ACP B-C、PGM1 1S-1F和GC 1S-2表型显著增加。特别是具有ACP B、PGM1 1S-1F和GC 1S-2表型的个体显示出最高的相对风险（RR）和归因风险（AR）值，似乎更容易患IDDM疾病。
