Pearce C B, McMeekin J D, Moyana T N, Sibley J
Royal University Hospital, Saskatoon, Canada.
Can J Cardiol. 1999 Apr;15(4):465-8.
A 19-year-old postpartum patient with a previous history of asthma and eosinophilic myocarditis is described. Eosinophilic myocarditis is thought to be caused by exacerbation of the idiopathic hypereosinophilic syndrome by pregnancy. The diagnosis was made by a right ventricular endomyocardial biopsy, which showed an eosinophilic infiltrate with a few scattered foci of myonecrosis, but no fibrosis, vasculitis or granulomas. The patient's myocardial function continued to decline over a two-year follow-up period, despite normal levels of eosinophils. She developed echocardiographic evidence of diastolic and systolic dysfunction.
本文描述了一名19岁的产后患者，她既往有哮喘和嗜酸性粒细胞性心肌炎病史。嗜酸性粒细胞性心肌炎被认为是由妊娠诱发的特发性嗜酸性粒细胞增多综合征加重所致。诊断通过右心室心内膜活检确定，活检显示有嗜酸性粒细胞浸润，伴有一些散在的心肌坏死灶，但无纤维化、血管炎或肉芽肿。尽管嗜酸性粒细胞水平正常，但在两年的随访期内，患者的心肌功能持续下降。她出现了舒张功能和收缩功能障碍的超声心动图证据。
