[南京地区荚膜组织胞浆菌感染的流行病学调查]

[Investigation on the epidemiology of Histoplasma capsulatum infection in Nanjing district].

作者信息

Zhao B, Yin J, Xia X

机构信息

Department of Respiratory Medicine, Nanjing General Hospital of Nanjing Command.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 1998 Aug;19(4):215-7.

PMID:10322674

Abstract

Two hundred and ninety-two permanent or temporary residents in Nanjing district were tested with histoplasmin (Histolyn-CYL, ALK/Berkeley Laboratories, USA) and PPD. Forty-nine (16.78%) subjects reacted to histoplasmin with 5.0-23.0 (9.5 +/- 4.2) mm induration. Positive reaction rate among people without pulmonary diseases (normal group) was 15.10% comparing to 17.74% to patients with pulmonary diseases. Positive reaction to PPD with 5-50 (14.2 +/- 4.7) mm induration was 56.16%, with 59.43% in normal group and 54.30% in patients with pulmonary diseases while 8.90% subjects reacted to both histoplasmin and PPD, 7.88% of the research subjects reacted to histoplasmin but not to PPD. Result suggested that there was herd infection of Histoplasma capsulatum in Nanjing district.

摘要

对南京地区292名永久或临时居民进行了组织胞浆菌素（美国ALK/伯克利实验室的Histolyn - CYL）和结核菌素纯蛋白衍生物（PPD）检测。49名（16.78%）受试者对组织胞浆菌素有反应，硬结直径为5.0 - 23.0（9.5±4.2）毫米。无肺部疾病人群（正常组）的阳性反应率为15.10%，而肺部疾病患者为17.74%。对PPD硬结直径为5 - 50（14.2±4.7）毫米的阳性反应率为56.16%，正常组为59.43%，肺部疾病患者为54.30%，8.90%的受试者对组织胞浆菌素和PPD均有反应，7.88%的研究对象对组织胞浆菌素有反应但对PPD无反应。结果表明南京地区存在荚膜组织胞浆菌的群体感染。