[Relationship between blood glucose, insulin and hypertension in 60 obese children].

OBJECTIVE

To study the relationship between blood glucose, insulin and hypertension in children.

METHODS

Fasting serum glucose (GS), insulin (IS) and high-density lipoprotein (HDL) were determined in 60 obese children and 60 normal controls, and oral glucose tolerance test was performed for half of them.

RESULTS

It showed that there were no significant differences in fasting GS, HDL and GS after glucose load between the two groups, and fasting IS, IS after glucose load, an area and a ratio of IS to GS under the insulin curve all were higher in the obese group than those in the control one. There were 43 obese children (71.7%) with hypertension.

CONCLUSION

There existed hyper-insulinemia and insulin resistance in obese children and there also was close relationship between obesity and hypertension in them.