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60例肥胖儿童血糖、胰岛素与高血压的关系

[Relationship between blood glucose, insulin and hypertension in 60 obese children].

作者信息

Guo X, Li J, Ma G

机构信息

Capital Institute of Pediatrics, Beijing.

出版信息

Zhonghua Yu Fang Yi Xue Za Zhi. 1998 Jan;32(1):25-7.

PMID:10322748
Abstract

OBJECTIVE

To study the relationship between blood glucose, insulin and hypertension in children.

METHODS

Fasting serum glucose (GS), insulin (IS) and high-density lipoprotein (HDL) were determined in 60 obese children and 60 normal controls, and oral glucose tolerance test was performed for half of them.

RESULTS

It showed that there were no significant differences in fasting GS, HDL and GS after glucose load between the two groups, and fasting IS, IS after glucose load, an area and a ratio of IS to GS under the insulin curve all were higher in the obese group than those in the control one. There were 43 obese children (71.7%) with hypertension.

CONCLUSION

There existed hyper-insulinemia and insulin resistance in obese children and there also was close relationship between obesity and hypertension in them.

摘要

目的

研究儿童血糖、胰岛素与高血压之间的关系。

方法

测定60例肥胖儿童和60例正常对照儿童的空腹血清葡萄糖(GS)、胰岛素(IS)和高密度脂蛋白(HDL),并对其中一半儿童进行口服葡萄糖耐量试验。

结果

结果显示,两组儿童空腹GS、HDL及葡萄糖负荷后GS无显著差异,肥胖组空腹IS、葡萄糖负荷后IS、胰岛素曲线下面积及IS与GS比值均高于对照组。43例肥胖儿童(71.7%)患有高血压。

结论

肥胖儿童存在高胰岛素血症和胰岛素抵抗,肥胖与高血压之间也存在密切关系。

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