He J P, Wang C B
302 Hospital of PLA, Beijing.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1997 Sep;17(9):540-1.
To study the curative effect of Chinese medicine in treating severe cholestatic-hepatitis (SCH).
Three hundred and fifty patients of SCH with total bilirubin level > or = 171 mumol/L were treated with Chinese medicines. For those with Blood Stasis Syndrome, treated with the recipe mainly consisted of Radix Paeoniae Rubra, and for which accompanied with blood Heat, fluid retention in epigastric region. Dampness dissenubated in Sanjiao ([symbol: see text]) or both Spleen and Kidney Yang-Deficiency Syndrome, the recipe was used in modification according to the Syndrome.
Treatment was markedly effective in 288 cases and effective in 26 cases, the total effective rate being 89.7%.
It is difficult in treating severe cholestatic hepatitis, especially the chronic cholestatic hepatitis, which could develop to severe chronic hepatitis if the jaundice lasted for a long time. This study showed a good effect of Chinese herbal medicine in eliminating jaundice.
研究中药治疗重度胆汁淤积性肝炎(SCH)的疗效。
对350例总胆红素水平≥171μmol/L的SCH患者采用中药治疗。对于有血瘀证者,以赤芍为主方治疗,兼有血热、胃脘水饮者,若三焦([符号:见正文])湿邪未清或兼有脾肾阳虚证,则根据证型对药方进行加减。
显效288例,有效26例,总有效率为89.7%。
重度胆汁淤积性肝炎,尤其是慢性胆汁淤积性肝炎治疗困难,若黄疸持续时间长可发展为重度慢性肝炎。本研究表明中药在退黄方面疗效良好。