Gregory J, Emslie A, Wyllie J, Wren C
Department of Community Paediatrics, Newcastle City Health NHS Trust.
Arch Dis Child Fetal Neonatal Ed. 1999 Jan;80(1):F46-8. doi: 10.1136/fn.80.1.f46.
To attempt to define the prevalence and significance of murmurs detected on routine clinical examination at six to eight weeks.
A retrospective review of the results of routine clinical examination of a cohort of 6 to 8 week old babies resident in Newcastle upon Tyne, was carried out in two 12 month periods. All cardiac defects diagnosed in infancy in the same cohort were ascertained.
7132 babies were eligible for routine examination; 83% of these were examined. Murmurs were heard in 47 of 5395 babies and in 11 of 25 referred for evaluation congenital heart disease was found. The six to eight week examination led to diagnosis of 11 of 35 cases (31%) of congenital heart disease in the study population.
Nearly one baby in 100 had a murmur on routine examination at six to eight weeks. Nearly half of those with murmurs who were referred had a structural cardiovascular malformation.
试图确定在6至8周龄时常规临床检查中发现的杂音的发生率及意义。
在两个12个月期间，对居住在泰恩河畔纽卡斯尔的一组6至8周龄婴儿的常规临床检查结果进行回顾性分析。确定同一队列中婴儿期诊断出的所有心脏缺陷。
7132名婴儿符合常规检查条件；其中83%接受了检查。在5395名婴儿中有47名听到杂音，在转诊评估的25名婴儿中有11名被发现患有先天性心脏病。在研究人群中，6至8周龄检查诊断出35例先天性心脏病中的11例（31%）。
在6至8周龄的常规检查中，近100名婴儿中有1名有杂音。转诊的有杂音婴儿中近一半患有结构性心血管畸形。
