Savluchinske Feio S, Gigante B, Roseiro J C, Marcelo-Curto M J
Instituto Nacional de Engenharia e Tecnologia Industrial, IBQTA, Laboratório de Microbiologia Industrial, Azinhaga dos Lameiros, Lisboa, Portugal.
J Microbiol Methods. 1999 Apr;35(3):201-6. doi: 10.1016/s0167-7012(98)00117-1.
C-13 deisopropylated and/or C-7 oxidized resin acid derivatives were tested against various microorganisms to determine structural features responsible for biological activity and to determine the influence of the C-13 isopropyl group on antimicrobial activity. Test results show that methyl cis and trans 7-oxo-13-deisopropyldehydroabietate and a mixture of both isomers exhibited activity against fungi and bacteria.
对C-13去异丙基化和/或C-7氧化的树脂酸衍生物进行了针对各种微生物的测试，以确定具有生物活性的结构特征，并确定C-13异丙基对抗菌活性的影响。测试结果表明，顺式和反式甲基7-氧代-13-去异丙基脱氢枞酸酯以及这两种异构体的混合物对真菌和细菌均表现出活性。
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