Hashimoto M, Kuwahara M, Tsubone H, Sugano S
Department of Comparative Pathophysiology, Graduate School of Agriculture and Life Sciences, The University of Tokyo, Japan.
J Electrocardiol. 1999 Apr;32(2):167-71.
We studied the diurnal variations of autonomic nervous function in rats. For this purpose, a long-term electrocardiogram (ECG) was recorded from conscious and unrestrained rats using a telemetry system, and the autonomic nervous function was investigated by the power spectral analysis of heart rate variability. No arrhythmias were observed in the ECG of any of the rats. Nocturnal patterns, in which the values of heart rate in the dark phase (2000-0600) were higher than those in the light phase (0600-2000), were observed. All normal rats shared a characteristic pattern in their power spectrum analysis. Both low-frequency and high-frequency power in the light phase were higher than those in the dark phase. However, these differences were not statistically significant (P > .05). The low frequency to high frequency ratio also showed a nocturnal pattern. The value in the dark phase was significantly higher (P < .05) than that in the light phase. These results suggest that the sympathetic nervous activity is predominant in the dark phase in rats. Therefore, we believe that this information may be useful for future biobehavioral studies.
我们研究了大鼠自主神经功能的昼夜变化。为此，使用遥测系统从清醒且不受束缚的大鼠记录长期心电图（ECG），并通过心率变异性的功率谱分析来研究自主神经功能。在任何大鼠的心电图中均未观察到心律失常。观察到夜间模式，即黑暗阶段（20:00 - 06:00）的心率值高于光照阶段（06:00 - 20:00）。所有正常大鼠在其功率谱分析中都有一个特征模式。光照阶段的低频和高频功率均高于黑暗阶段。然而，这些差异无统计学意义（P > 0.05）。低频与高频比值也呈现夜间模式。黑暗阶段的值显著高于光照阶段（P < 0.05）。这些结果表明，大鼠在黑暗阶段交感神经活动占主导。因此，我们认为该信息可能对未来的生物行为学研究有用。
Zotero 插件