Durzyński T, Konopka L, Traczyk Z
Wewnetrznych Instytutu Hematologii i Transfuzjologii, Kliniki Chorób.
Pol Merkur Lekarski. 1999 Jan;6(31):30-1.
The leukostasis syndrome is rare complication of leukemias with extremely high white cell counts. It occurs most frequently in chronic myelosis or acute leukemias and is exceptional in chronic lymphocytic leukemia (CLL). A severe leukostasis syndrome was observed in a case of CLL with peripheral lymphocyte count of 1,120 G/L. Typical symptoms of respiratory and central nervous system were developed (tachypnoe, hypoxia, headache, slurred speech, somnolence and confusion). Leukapheresis decreased the lymphocyte count to 305 G/l rapidly and reversed the leukostasis syndrome.
白细胞淤滞综合征是白血病中白细胞计数极高时罕见的并发症。它最常发生于慢性粒细胞白血病或急性白血病,在慢性淋巴细胞白血病(CLL)中较为罕见。在1例外周淋巴细胞计数为1120 G/L的CLL患者中观察到严重的白细胞淤滞综合征。出现了典型的呼吸和中枢神经系统症状(呼吸急促、缺氧、头痛、言语不清、嗜睡和意识模糊)。白细胞单采术迅速将淋巴细胞计数降至305 G/L,并逆转了白细胞淤滞综合征。