Bláha M, Jebavý L, Malý J, Filip S, Kmonícek M, Siroký O
Vojenská lékarská akademie JEP Hradec Králové.
Vnitr Lek. 1993 Aug;39(8):788-92.
The authors draw attention to the leukostasis syndrome which develops in haematological patients in case of enormous leucocyte proliferation. It occurs most frequently in chronic myelosis but may occur also in other types of leukaemia. The diagnosis is not easy. Most frequently disorders of the microcirculation develop in the lungs and brain. These are frequently very urgent clinical situations which can be resolved by leukapheresis. The authors described a patient where during chronic lymphadenosis proliferation of lymphocytes occurred to values of 1432 x 10(9)/l. After leukapheresis and cytostatic treatment rapid improvement of the condition occurred and the leucocyte values were approximately 30 x 10(9)/l. The patient's condition improved for a long period of time and became stabilized.
作者提请注意血液学患者在白细胞大量增殖时发生的白细胞淤滞综合征。它最常发生于慢性粒细胞白血病，但也可能发生于其他类型的白血病。诊断并不容易。最常见的是肺部和脑部出现微循环障碍。这些常常是非常紧急的临床情况，可通过白细胞单采术解决。作者描述了一名患者，在慢性淋巴结病期间淋巴细胞增殖至1432×10⁹/L。白细胞单采术和细胞抑制治疗后病情迅速改善，白细胞值约为30×10⁹/L。患者病情长期改善并稳定下来。
