Birtles R J, Canales J, Ventosilla P, Alvarez E, Guerra H, Llanos-Cuentas A, Raoult D, Doshi N, Harrison T G
Unité de Rickettsies, CNRS EPJ0054, Faculté de Medécine, Marseille, France.
Am J Trop Med Hyg. 1999 May;60(5):799-805. doi: 10.4269/ajtmh.1999.60.799.
The natural cycle of Bartonella bacilliformis remains uncertain, and the suspected existence of animal reservoirs for the bacterium has never been convincingly demonstrated. We conducted a survey of Bartonella species infecting intradomicillary animals in a bartonellosis-endemic region of Peru, obtaining blood from 50 animals living in the homes of 11 families whose children had recently had bartonellosis. Bartonella-like bacteria were recovered from four of nine small rodents included in the study, but from none of the 41 domesticated animals. Identification and comparison of these isolates, and two Bartonella-like isolates obtained from Phyllotis mice in a different endemic region of Peru using serologic and genotypic methods indicated that although none were strains of B. bacilliformis, five were probably representatives of three previously unrecognized Bartonella species and one was a likely strain of the pathogenic species B. elizabethae.
杆菌状巴尔通体的自然循环仍不明确，而且从未有令人信服的证据证明该细菌存在动物宿主。我们在秘鲁巴尔通体病流行地区对感染家养动物的巴尔通体菌种进行了一项调查，从11个家庭的家中生活的50只动物身上采集血液，这些家庭的孩子近期患有巴尔通体病。在纳入研究的9只小型啮齿动物中，有4只检测出了类巴尔通体细菌，但41只家养动物中均未检测出。使用血清学和基因分型方法对这些分离株以及从秘鲁另一个流行地区的叶耳鼠身上获得的2个类巴尔通体分离株进行鉴定和比较，结果表明，虽然没有一个是杆菌状巴尔通体菌株，但有5个可能是3种先前未被识别的巴尔通体菌种的代表，1个可能是致病性伊丽莎白巴尔通体的菌株。
