Kern M J, Aguirre F V, Caracciolo E A, Bach R G, Donohue T J, Lasorda D, Ohman E M, Schnitzler R N, King D L, Ohley W J, Grayzel J
Saint Louis University Health Sciences Center, St. Louis, MO 63110, USA.
Am Heart J. 1999 Jun;137(6):1129-36. doi: 10.1016/s0002-8703(99)70373-x.
To test whether later intra-aortic balloon pump (IABP) deflation approaching or simultaneous with left ventricular ejection would improve hemodynamics and myocardial efficiency with the use of new balloon deflation methods, 4 IABP timing techniques were evaluated in 43 patients.
Later balloon deflation produced significantly greater percentage changes in mean aortic pressure (6% vs 1%), systolic pressure time index (-27% vs -20%), diastolic pressure time index (35% vs 19%), and the systolic pressure-time index/diastolic pressure-time index ratio (97% vs 51%), respectively. However, these changes increased peak systolic pressure (-15% vs -11%). Cardiac output and stroke volume indexes were not significantly altered over the 4 settings.
These data suggest that systemic hemodynamics and myocardial efficiency may be improved by later balloon deflation approaching left ventricular ejection in comparison to conventional IABP timing.
为了测试采用新的球囊放气方法时，主动脉内球囊反搏（IABP）在接近左心室射血或与左心室射血同时放气是否会改善血流动力学和心肌效率，对43例患者评估了4种IABP计时技术。
延迟球囊放气分别使平均主动脉压的百分比变化（6%对1%）、收缩压时间指数（-27%对-20%）、舒张压时间指数（35%对19%）以及收缩压时间指数/舒张压时间指数比值（97%对51%）显著更大。然而，这些变化使收缩压峰值升高（-15%对-11%）。在这4种设置下，心输出量和每搏量指数没有显著改变。
这些数据表明，与传统的IABP计时相比，接近左心室射血时延迟球囊放气可能会改善全身血流动力学和心肌效率。
