Peptide antibiotics.
作者信息
Hancock R E, Chapple D S
机构信息
Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z3.
出版信息
Antimicrob Agents Chemother. 1999 Jun;43(6):1317-23. doi: 10.1128/AAC.43.6.1317.
Abstract
摘要
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The therapeutic potential of cationic peptides.阳离子肽的治疗潜力。
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Mechanism of interaction of different classes of cationic antimicrobial peptides with planar bilayers and with the cytoplasmic membrane of Escherichia coli.不同类别的阳离子抗菌肽与平面双层膜及大肠杆菌细胞质膜的相互作用机制
Biochemistry. 1999 Jun 1;38(22):7235-42. doi: 10.1021/bi9826299.
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Interaction of the cyclic antimicrobial cationic peptide bactenecin with the outer and cytoplasmic membrane.环状抗菌阳离子肽杆菌防御素与外膜和细胞质膜的相互作用。
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Structure-function relationship of antibacterial synthetic peptides homologous to a helical surface region on human lactoferrin against Escherichia coli serotype O111.与人乳铁蛋白螺旋表面区域同源的抗菌合成肽对大肠杆菌O111血清型的结构-功能关系
Infect Immun. 1998 Jun;66(6):2434-40. doi: 10.1128/IAI.66.6.2434-2440.1998.
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Targeted alteration of the substrate specificity of peptide synthetases by rational module swapping.通过合理的模块交换对肽合成酶的底物特异性进行定向改造。
Mol Gen Genet. 1998 Feb;257(3):308-18. doi: 10.1007/s004380050652.
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Instruments of microbial warfare: bacteriocin synthesis, toxicity and immunity.微生物战的武器：细菌素的合成、毒性及免疫
Trends Microbiol. 1998 Feb;6(2):66-71. doi: 10.1016/S0966-842X(97)01196-7.
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Cationic peptides: a new source of antibiotics.阳离子肽：抗生素的新来源。
Trends Biotechnol. 1998 Feb;16(2):82-8. doi: 10.1016/s0167-7799(97)01156-6.
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Design of synthetic antimicrobial peptides based on sequence analogy and amphipathicity.基于序列相似性和两亲性的合成抗菌肽设计。
Eur J Biochem. 1997 Dec 1;250(2):549-58. doi: 10.1111/j.1432-1033.1997.0549a.x.
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Drosophila host defense: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms.果蝇的宿主防御：感染各类微生物后抗菌肽基因的差异诱导。
Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14614-9. doi: 10.1073/pnas.94.26.14614.
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