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Peptide antibiotics.肽类抗生素
Antimicrob Agents Chemother. 1999 Jun;43(6):1317-23. doi: 10.1128/AAC.43.6.1317.
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Posttranslationally modified bacteriocins--the lantibiotics.翻译后修饰的细菌素——羊毛硫抗生素。
Biopolymers. 2000;55(1):62-73. doi: 10.1002/1097-0282(2000)55:1<62::AID-BIP60>3.0.CO;2-Y.
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Therapeutic potential of type A (I) lantibiotics, a group of cationic peptide antibiotics.A型(I)羊毛硫抗生素(一类阳离子肽抗生素)的治疗潜力
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Class II antimicrobial peptides from lactic acid bacteria.来自乳酸菌的II类抗菌肽。
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Structure of microcin C51, a new antibiotic with a broad spectrum of activity.微菌素C51的结构,一种具有广泛活性谱的新型抗生素。
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[Lantibiotics, a class of ribosomally synthesized peptide antibiotics].[羊毛硫抗生素,一类核糖体合成的肽抗生素]
Naturwissenschaften. 1993 Oct;80(10):454-60. doi: 10.1007/BF01136035.
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Cationic peptides: effectors in innate immunity and novel antimicrobials.阳离子肽:固有免疫效应分子与新型抗菌剂
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Synthetic peptides derived from the sequence of a lasso peptide microcin J25 show antibacterial activity.从微菌素 J25 的序列衍生的合成肽显示出抗菌活性。
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Biosynthesis and mode of action of lantibiotics.羊毛硫抗生素的生物合成及作用方式。
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Plant defensins: novel antimicrobial peptides as components of the host defense system.植物防御素:作为宿主防御系统组成部分的新型抗菌肽。
Plant Physiol. 1995 Aug;108(4):1353-8. doi: 10.1104/pp.108.4.1353.

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Antimicrobial Peptides: Mechanisms, Applications, and Therapeutic Potential.抗菌肽:作用机制、应用及治疗潜力
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Advances of Peptides for Plant Immunity.用于植物免疫的肽的进展
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Human amylin is a potent antimicrobial peptide that exhibits antimicrobial synergism with the amyloid beta protein.人胰岛淀粉样多肽是一种有效的抗菌肽,与β-淀粉样蛋白具有抗菌协同作用。
Alzheimers Dement. 2025 Aug;21(8):e70490. doi: 10.1002/alz.70490.
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Enhancing the selectivity and conditional sensitivity of an antimicrobial peptide through cleavage simulations and homoarginine incorporation to combat drug-resistant bacteria.通过裂解模拟和高精氨酸掺入提高抗菌肽的选择性和条件敏感性以对抗耐药细菌。
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Cationic antimicrobial peptides: potential templates for anticancer agents.阳离子抗菌肽:抗癌药物的潜在模板。
Front Med (Lausanne). 2025 Apr 24;12:1548603. doi: 10.3389/fmed.2025.1548603. eCollection 2025.
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Evolutionary trajectory of bacterial resistance to antibiotics and antimicrobial peptides in .细菌对抗生素和抗菌肽耐药性的进化轨迹 于……(原文此处不完整)
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Role of Divalent Ions in Membrane Models of Polymyxin-Sensitive and Resistant Gram-Negative Bacteria.二价离子在多粘菌素敏感和耐药革兰氏阴性菌膜模型中的作用
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Multidrug resistant : A study on its pathogenesis and therapeutics.多重耐药性:其发病机制与治疗方法的研究
Curr Res Microb Sci. 2024 Dec 6;8:100331. doi: 10.1016/j.crmicr.2024.100331. eCollection 2025.
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Amphibian-Derived Antimicrobial Peptides: Essential Components of Innate Immunity and Potential Leads for New Antibiotic Development.两栖动物源抗菌肽:固有免疫的重要组成部分及新型抗生素开发的潜在先导物
Protein Pept Lett. 2025;32(2):97-110. doi: 10.2174/0109298665356946241218103145.

本文引用的文献

1
Drosophila immunity.果蝇免疫。
Trends Cell Biol. 1997 Aug;7(8):309-16. doi: 10.1016/S0962-8924(97)01087-8.
2
The therapeutic potential of cationic peptides.阳离子肽的治疗潜力。
Expert Opin Investig Drugs. 1998 Feb;7(2):167-74. doi: 10.1517/13543784.7.2.167.
3
Mechanism of interaction of different classes of cationic antimicrobial peptides with planar bilayers and with the cytoplasmic membrane of Escherichia coli.不同类别的阳离子抗菌肽与平面双层膜及大肠杆菌细胞质膜的相互作用机制
Biochemistry. 1999 Jun 1;38(22):7235-42. doi: 10.1021/bi9826299.
4
Interaction of the cyclic antimicrobial cationic peptide bactenecin with the outer and cytoplasmic membrane.环状抗菌阳离子肽杆菌防御素与外膜和细胞质膜的相互作用。
J Biol Chem. 1999 Jan 1;274(1):29-35. doi: 10.1074/jbc.274.1.29.
5
Structure-function relationship of antibacterial synthetic peptides homologous to a helical surface region on human lactoferrin against Escherichia coli serotype O111.与人乳铁蛋白螺旋表面区域同源的抗菌合成肽对大肠杆菌O111血清型的结构-功能关系
Infect Immun. 1998 Jun;66(6):2434-40. doi: 10.1128/IAI.66.6.2434-2440.1998.
6
Targeted alteration of the substrate specificity of peptide synthetases by rational module swapping.通过合理的模块交换对肽合成酶的底物特异性进行定向改造。
Mol Gen Genet. 1998 Feb;257(3):308-18. doi: 10.1007/s004380050652.
7
Instruments of microbial warfare: bacteriocin synthesis, toxicity and immunity.微生物战的武器:细菌素的合成、毒性及免疫
Trends Microbiol. 1998 Feb;6(2):66-71. doi: 10.1016/S0966-842X(97)01196-7.
8
Cationic peptides: a new source of antibiotics.阳离子肽:抗生素的新来源。
Trends Biotechnol. 1998 Feb;16(2):82-8. doi: 10.1016/s0167-7799(97)01156-6.
9
Design of synthetic antimicrobial peptides based on sequence analogy and amphipathicity.基于序列相似性和两亲性的合成抗菌肽设计。
Eur J Biochem. 1997 Dec 1;250(2):549-58. doi: 10.1111/j.1432-1033.1997.0549a.x.
10
Drosophila host defense: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms.果蝇的宿主防御:感染各类微生物后抗菌肽基因的差异诱导。
Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14614-9. doi: 10.1073/pnas.94.26.14614.

Peptide antibiotics.

作者信息

Hancock R E, Chapple D S

机构信息

Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z3.

出版信息

Antimicrob Agents Chemother. 1999 Jun;43(6):1317-23. doi: 10.1128/AAC.43.6.1317.

DOI:10.1128/AAC.43.6.1317
PMID:10348745
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC89271/
Abstract
摘要