与选定的大环内酯类药物及其他药物相比，利奈唑胺对从人类软组织咬伤感染中分离出的需氧和厌氧病原体的活性。
Linezolid activity compared to those of selected macrolides and other agents against aerobic and anaerobic pathogens isolated from soft tissue bite infections in humans.
作者信息
Goldstein E J, Citron D M, Merriam C V
机构信息
R. M. Alden Research Laboratory, Santa Monica-UCLA Medical Center, Santa Monica, California 90404, USA.
出版信息
Antimicrob Agents Chemother. 1999 Jun;43(6):1469-74. doi: 10.1128/AAC.43.6.1469.
Abstract
Linezolid was tested against 420 aerobes and anaerobes, including 148 Pasteurella isolates, by an agar dilution method. Linezolid was active against all Pasteurella multocida subsp. multocida and P. multocida subsp. septica isolates and most Pasteurella canis, Pasteurella dagmatis, and Pasteurella stomatis isolates. The MIC was </=2 microg/ml for staphylococci, streptococci, EF-4b, Weeksella zoohelcum, Fusobacterium nucleatum, other fusobacteria, Porphyromonas spp., Prevotella spp., peptostreptococci, and almost all Bacteroides tectum isolates.
摘要
采用琼脂稀释法对包括148株巴斯德菌分离株在内的420株需氧菌和厌氧菌进行了利奈唑胺测试。利奈唑胺对所有多杀巴斯德菌多杀亚种和多杀巴斯德菌败血亚种分离株以及大多数犬巴斯德菌、龈巴斯德菌和口巴斯德菌分离株均有活性。葡萄球菌、链球菌、EF-4b、动物溃疡韦荣球菌、具核梭杆菌、其他梭杆菌、卟啉单胞菌属、普雷沃菌属、消化链球菌和几乎所有的脆弱拟杆菌分离株的最低抑菌浓度（MIC）≤2微克/毫升。
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本文引用的文献
1
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Anaerobe. 1997 Oct;3(5):301-6. doi: 10.1006/anae.1997.0115.
2
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N Engl J Med. 1999 Jan 14;340(2):85-92. doi: 10.1056/NEJM199901143400202.
3
The pharmacologic and bacteriologic properties of oxazolidinones, a new class of synthetic antimicrobials.恶唑烷酮类新型合成抗菌药物的药理学和细菌学特性
Pharmacotherapy. 1998 May-Jun;18(3):456-62.
4
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5
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6
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7
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10
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