Atkin N B
Cytobios. 1976;15(60):233-7.
The 5-year survival rate of 78 patients with carcinoma of the ovary showed that the prognosis was significantly better when the tumour modal DNA value was in the diploid region than when it was near-triploid or above. Similar data on 140 patients with carcinoma of the breast and 52 with carcinoma of the bladder also suggested a better prognosis for the near-diploid tumours. Among 105 carcinomas of the large bowel, however, there were more survivors in the high-ploidy than in the near-diploid group, although the difference was not statistically significant. The varying relationship between ploidy and prognosis, depending on the site or histological type of the tumour, is briefly discussed on the basis of the 1171 cases included in the present and a previous paper.
78例卵巢癌患者的5年生存率表明，肿瘤模态DNA值处于二倍体区域时的预后明显好于接近三倍体或高于三倍体时。140例乳腺癌患者和52例膀胱癌患者的类似数据也表明，接近二倍体肿瘤的预后更好。然而，在105例大肠癌中，高倍体组的存活者比接近二倍体组更多，尽管差异无统计学意义。基于本文及之前一篇论文中纳入的1171例病例，简要讨论了倍体与预后之间因肿瘤部位或组织学类型而异的关系。
