Vilkki J, Surma-aho O, Servo A
Department of Neurosurgery, Helsinki University Central Hospital, University of Helsinki, Finland.
Neuropsychology. 1999 Apr;13(2):298-305. doi: 10.1037//0894-4105.13.2.298.
This study partly supports the hypothesis that frontal lobe lesions cause impairment of metamemory. Fifty-nine patients with a focal brain lesion and 21 non-brain-damaged patients memorized a 4 X 4 matrix of 16 faces in 6 consecutive trials and predicted the number of locations of faces they would be able to remember before each retrieval. When age-related impairment of learning was adjusted, the patients with right posterior lesions were inferior to the controls and to the patients with right frontal lesions on the total number of correctly placed faces. The patients with right frontal lesions were less accurate than the patients with right posterior lesions or the controls in the prediction of retrieval. The inaccuracy of retrieval prediction in the face test was associated with that in a word-list learning task.
本研究部分支持了额叶病变会导致元记忆受损的假说。59名患有局灶性脑损伤的患者和21名未患脑损伤的患者连续6次试验记忆一个4×4矩阵中的16张面孔，并在每次检索前预测他们能够记住的面孔位置数量。在调整了与年龄相关的学习障碍后，右侧后部病变的患者在正确放置面孔的总数上比对照组和右侧额叶病变的患者差。右侧额叶病变的患者在检索预测方面不如右侧后部病变的患者或对照组准确。面孔测试中检索预测的不准确与单词列表学习任务中的不准确相关。
